Pilot-Scale Extraction Systems - Modular GMP-Compliant Solutions
System Overview
Broyue's integrated extraction modules provide scalable, GMP-compliant processing for botanical extracts, pharmaceuticals, and essential oils. Our systems bridge R&D to production with flexible operation modes.
Key Components
- Core Processing Modules
- Extraction Vessel:
- Jacketed heating (steam/oil thermal fluid)
- Built-in anti-foaming system
- Agitation options: Anchor/Turbine/Recirculation
- Evaporation-Condensation Unit:
- Falling film/centrifugal evaporators
- Low-temperature condensation (-10°C optional)
- Separation System:
- Liquid-liquid separators (essential oil recovery)
- Cyclone filters for particulate removal
- Support Systems
- Automated Controls:
- PLC/HMI with recipe management
- Real-time monitoring: Density, refractive index, pH
- Material Handling:
- Pneumatic conveying for herb input
- Slag discharge with screw conveyor
process capabilities
| Function | Technical highlights | Typical applications |
| Extraction | Dynamic /static maceration/percolation | Cannabinoids, herbal concentrates |
| Concentration | 40°C low-T vacuum evaporation | Heat-sensitive compounds |
| Distillation | Ethanol/water/solvent recovery (≥95%) | Essential oils, tinctures |
| Precipitation | In-line chilling (+2°C to -5°C) | Protein purification |
Scalability Options
Pilot Systems (R&D Focus)
- Compact skid-mounted designs
- Quick-change vessel configurations
- Data logging for process development
Production Systems
- Multi-vessel parallel operation (2-8 units)
- Centralized automation:
- OEE tracking
- CIP integration
- Custom layouts for existing facilities
GMP Design Features
✔ Sanitary construction: Orbital welding, drainable angles
✔ Material traceability: Full documentation packages
✔ Validation support: IQ/OQ/PQ protocols
✔ Cleanability: CIP-ready with spray devices
Industry Applications
- Phytopharmaceuticals: Active ingredient extraction
- Nutraceuticals: Standardized herbal extracts
- Essential Oils: Terpene fractionation
- Biotech: Natural product isolation
