Pilot-Scale Extraction Systems – Modular GMP-Compliant Solutions
System Overview
Broyue’s integrated extraction modules provide scalable, GMP-compliant processing for botanical extracts, pharmaceuticals, and essential oils. Our systems bridge R&D to production with flexible operation modes.
Key Components
- Core Processing Modules
– Extraction Vessel:
– Jacketed heating (steam/oil thermal fluid)
– Built-in anti-foaming system
– Agitation options: Anchor/Turbine/Recirculation
– Evaporation-Condensation Unit:
– Falling film/centrifugal evaporators
– Low-temperature condensation (-10°C optional)
– Separation System:
– Liquid-liquid separators (essential oil recovery)
– Cyclone filters for particulate removal
- Support Systems
– Automated Controls:
– PLC/HMI with recipe management
– Real-time monitoring: Density, refractive index, pH
– Material Handling:
– Pneumatic conveying for herb input
– Slag discharge with screw conveyor
process capabilities
| Function | Technical highlights | Typical applications |
| Extraction | Dynamic /static maceration/percolation | Cannabinoids, herbal concentrates |
| Concentration | 40°C low-T vacuum evaporation | Heat-sensitive compounds |
| Distillation | Ethanol/water/solvent recovery (≥95%) | Essential oils, tinctures |
| Precipitation | In-line chilling (+2°C to -5°C) | Protein purification |
Scalability Options
Pilot Systems (R&D Focus)
– Compact skid-mounted designs
– Quick-change vessel configurations
– Data logging for process development
Production Systems
– Multi-vessel parallel operation (2-8 units)
– Centralized automation:
– OEE tracking
– CIP integration
– Custom layouts for existing facilities
GMP Design Features
✔ Sanitary construction: Orbital welding, drainable angles
✔ Material traceability: Full documentation packages
✔ Validation support: IQ/OQ/PQ protocols
✔ Cleanability: CIP-ready with spray devices
Industry Applications
– Phytopharmaceuticals: Active ingredient extraction
– Nutraceuticals: Standardized herbal extracts
– Essential Oils: Terpene fractionation
– Biotech: Natural product isolation
